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Editors' Highlights

2020 Research Highlights

As the field’s leading Open Access neuroscience journal, Molecular Neurodegeneration showcases research focusing on the molecular and cellular mechanisms underlying neurodegenerative diseases.

Now in our 15th year of publication, our Editors would like to share a selection of recent article highlights.

New Content ItemLongitudinal and nonlinear relations of dietary and Serum cholesterol in midlife with cognitive decline: results from EMCOA study 

Yu An, Xiaona Zhang, […] Rong Xiao 

New Content Item © © unoL / Getty Images / iStockGenetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer’s disease 

Ravi S. Pandey, Leah Graham, […] Gregory W. Carter

New Content ItemSynergistic effects of APOE and sex on the gut microbiome of young EFAD transgenic mice.  

Juan Maldonado Weng, Ishita Parikh, […] Mary Jo LaDu

New Content ItemAutophagy protein NRBF2 has reduced expression in Alzheimer’s brains and modulates memory and amyloid-beta homeostasis in mice

Véronik Lachance, Qian Wang, […] Zhenyu Yue

New Content ItemTargeting tauopathy with engineered tau-degrading intrabodies

Gilbert Gallardo, Connie H. Wong, […] David M. Holtzman.


New Content ItemLack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model

Tien-Phat V. Huynh, Chao Wang, […] David M. Holtzman. 

New Content ItemMicroglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson’s disease

Sonia George, Nolwen L. Rey, […] Patrik Brundin

New Content Item © © koto_feja / Getty Images / iStockSynaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade

Erica Acquarone, Elentina K. Argyrousi, […] Fiorito

New Content ItemDifferential effects of diet- and genetically-induced brain insulin resistance on amyloid pathology in a mouse model of Alzheimer’s disease 

Tomoko Wakabayashi, Kazuki Yamaguchi, […] Takeshi Iwatsubo 

New Content ItemFunctional networks are impaired by elevated tau-protein but reversible in a regulatable Alzheimer’s disease mouse model

Claudia Green, Astrid Sydow, […] Mathias Hoehn

New Content ItemDural lymphatics regulate clearance of extracellular tau from the CNS

Tirth K. Patel, LeMoyne Habimana-Griffin, […] David M. Holtzman

New Content ItemAberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Jeannie Chew, Casey Cook, […] Leonard Petrucelli

New Content ItemEarly increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

Marc Suárez-Calvet, Estrella Morenas-Rodríguez, […] Christian Haass & for the Alzheimer’s Disease Neuroimaging Initiative

Molecular Neurodegeneration is the official journal of the BrightFocus Foundation.


Editors-in-Chief

Guojun Bu, Mayo Clinic, USA

Huaxi Xu, Sanford Burnham Prebys Medical Discovery Institute, USA

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