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Figure 6 | Molecular Neurodegeneration

Figure 6

From: Presenilin-dependent intramembrane cleavage of ephrin-B1

Figure 6

Proteolytic processing of overexpressed eB1ΔE derivatives. Cell-free assay using COS membranes expressing eB1ΔEΔtag (left), eB1ΔEΔtagΔYKV (middle) and eB1ΔEΔ34 (right). Antibodies used were indicated below the panels. All derivatives (arrowheads) were cleaved to generate ICD-like peptides (asterisks) by γ-secretase activity.

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