Figure 4From: Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expressionCompounds that reduce tau protein levels also affect mRNA expression. H4 cells were treated in triplicate with 10, 1, and 0.1 μM of compounds listed on x-axis. Quantitative real time PCR was used to determine expression levels of tau relative to GAPDH. Relative fluorescent units (RFUs) were determined and presented here as a percentage of the vehicle-treated controls. "NS" indicates no RFUs detected.Back to article page