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Figure 1 | Molecular Neurodegeneration

Figure 1

From: Bcl-2 over-expression fails to prevent age-related loss of calretinin positive neurons in the mouse dentate gyrus

Figure 1

Over-expression of Human Bcl-2 in the mouse hippocampus. A) Western-blots of the hippocampal lysates from 18 month-old C57BL/6J (WT, two mice) and NSE73a transgenic mice (Hu-Bcl-2, two mice). B) Co-localization of the transgenic Bcl-2 and CR in the hippocampus. Four layers of the mouse dentate gyrus are labeled on the overlay: M, molecular layer; G, granule cell layer; SGZ, sub-granule cell zone; and H, Hilus. The whole calibration length is 25 μm.

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