Figure 3

Proliferation rate of adult neurogenesis using Ki-67 as a marker. A) One example of GFP (green) and Ki-67 (red) in a 2 month-old mouse dentate gyrus. The whole calibration bar is 25 μm. B)Semi-quantification of Ki-67 positive cells in both wild-type (2 month-old, n = 3; 24-month-old, n = 3) and NSE73a transgenic mice (2 month-old, n = 3; 24-month-old, n = 3) (+/- SE). Based on two-way ANOVA, There was a statistical difference between two age groups (P = 0.004), but there was no difference between two genotypes (P = 0.541), and also no a statistically significant interaction between genotype and age (P = 0.410).