Figure 6From: Bcl-2 over-expression fails to prevent age-related loss of calretinin positive neurons in the mouse dentate gyrusAge-related decease of CR positive cells at the SGZ. A)Dramatic decrease of CR positive cells at the SGZ during aging. The whole calibration bar is 25 μm. B) Semi-quantification of CR positive cells at the SGZ in both wild-type (total 9 mice, 3 for each age group) and NSE73a transgenic mice (total 9 mice, 3 for each age group) (+/- SE). Based on two-way ANOVA, There was a statistical difference between two age groups (P = 0.001), between two genotypes (P = 0.002), and a significant interaction between genotype and age (P = 0.049).Back to article page