TY - JOUR AU - Kravtsova Ivantsiv, Y. AU - Sommer, T. AU - Ciechanover, A. PY - 2012 DA - 2012// TI - The lysine48-based polyubiquitin chain proteasomal signal: not a single child anymore JO - Angew Chem Int Ed Engl VL - 52 UR - https://doi.org/10.1002/anie.201205656 DO - 10.1002/anie.201205656 ID - Kravtsova Ivantsiv2012 ER - TY - JOUR AU - Welchman, R. L. AU - Gordon, C. AU - Mayer, R. J. PY - 2005 DA - 2005// TI - Ubiquitin and ubiquitin-like proteins as multifunctional signals JO - Nat Rev Mol Cell Biol VL - 6 UR - https://doi.org/10.1038/nrm1700 DO - 10.1038/nrm1700 ID - Welchman2005 ER - TY - JOUR AU - Lauwers, E. AU - Jacob, C. AU - Andre, B. PY - 2009 DA - 2009// TI - K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway JO - J Cell Biol VL - 185 UR - https://doi.org/10.1083/jcb.200810114 DO - 10.1083/jcb.200810114 ID - Lauwers2009 ER - TY - JOUR AU - Zhou, A. Y. AU - Shen, R. R. AU - Kim, E. AU - Lock, Y. J. AU - Xu, M. AU - Chen, Z. J. PY - 2013 DA - 2013// TI - IKKepsilon-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex JO - Cell Reports VL - 3 UR - https://doi.org/10.1016/j.celrep.2013.01.031 DO - 10.1016/j.celrep.2013.01.031 ID - Zhou2013 ER - TY - JOUR AU - Schmukle, A. C. AU - Walczak, H. PY - 2012 DA - 2012// TI - No one can whistle a symphony alone - how different ubiquitin linkages cooperate to orchestrate NF-kappaB activity JO - J Cell Sci VL - 125 UR - https://doi.org/10.1242/jcs.091793 DO - 10.1242/jcs.091793 ID - Schmukle2012 ER - TY - JOUR AU - Humphrey, R. K. AU - Yu, S. M. AU - Bellary, A. AU - Gonuguntla, S. AU - Yebra, M. AU - Jhala, U. S. PY - 2013 DA - 2013// TI - Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 scaffold protein in cytokine-induced pancreatic beta cell death JO - J Biol Chem VL - 288 UR - https://doi.org/10.1074/jbc.M112.425884 DO - 10.1074/jbc.M112.425884 ID - Humphrey2013 ER - TY - JOUR AU - Kraut, D. A. AU - Prakash, S. AU - Matouschek, A. PY - 2007 DA - 2007// TI - To degrade or release: ubiquitin-chain remodeling JO - Trends Cell Biol VL - 17 UR - https://doi.org/10.1016/j.tcb.2007.06.008 DO - 10.1016/j.tcb.2007.06.008 ID - Kraut2007 ER - TY - JOUR AU - Lee, M. J. AU - Lee, B. H. AU - Hanna, J. AU - King, R. W. AU - Finley, D. PY - 2010 DA - 2010// TI - Trimming of ubiquitin chains by proteasome-associated deubiquitinating enzyme JO - Mol Cell Proteomics VL - 10 ID - Lee2010 ER - TY - JOUR AU - Anderson, C. AU - Crimmins, S. AU - Wilson, J. A. AU - Korbel, G. A. AU - Ploegh, H. L. AU - Wilson, S. M. PY - 2005 DA - 2005// TI - Loss of Usp14 results in reduced levels of ubiquitin in ataxia mice JO - J Neurochem VL - 95 UR - https://doi.org/10.1111/j.1471-4159.2005.03409.x DO - 10.1111/j.1471-4159.2005.03409.x ID - Anderson2005 ER - TY - JOUR AU - Hanna, J. AU - Hathaway, N. A. AU - Tone, Y. AU - Crosas, B. AU - Elsasser, S. AU - Kirkpatrick, D. S. PY - 2006 DA - 2006// TI - Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation JO - Cell VL - 127 UR - https://doi.org/10.1016/j.cell.2006.07.038 DO - 10.1016/j.cell.2006.07.038 ID - Hanna2006 ER - TY - JOUR AU - Lee, B. H. AU - Lee, M. J. AU - Park, S. AU - Oh, D. C. AU - Elsasser, S. AU - Chen, P. C. PY - 2010 DA - 2010// TI - Enhancement of proteasome activity by a small-molecule inhibitor of USP14 JO - Nature VL - 467 UR - https://doi.org/10.1038/nature09299 DO - 10.1038/nature09299 ID - Lee2010 ER - TY - JOUR AU - Peth, A. AU - Besche, H. C. AU - Goldberg, A. L. PY - 2009 DA - 2009// TI - Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening JO - Mol Cell VL - 36 UR - https://doi.org/10.1016/j.molcel.2009.11.015 DO - 10.1016/j.molcel.2009.11.015 ID - Peth2009 ER - TY - JOUR AU - Tian, Z. AU - D’Arcy, P. AU - Wang, X. AU - Ray, A. AU - Tai, Y. T. AU - Hu, Y. PY - 2014 DA - 2014// TI - A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance JO - Blood VL - 123 UR - https://doi.org/10.1182/blood-2013-05-500033 DO - 10.1182/blood-2013-05-500033 ID - Tian2014 ER - TY - JOUR AU - D’Arcy, P. AU - Brnjic, S. AU - Olofsson, M. H. AU - Fryknas, M. AU - Lindsten, K. AU - De Cesare, M. PY - 2011 DA - 2011// TI - Inhibition of proteasome deubiquitinating activity as a new cancer therapy JO - Nat Med VL - 17 UR - https://doi.org/10.1038/nm.2536 DO - 10.1038/nm.2536 ID - D’Arcy2011 ER - TY - JOUR AU - Jung, H. AU - Kim, B. G. AU - Han, W. H. AU - Lee, J. H. AU - Cho, J. Y. AU - Park, W. S. PY - 2013 DA - 2013// TI - Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling JO - Oncogenesis VL - 2 UR - https://doi.org/10.1038/oncsis.2013.28 DO - 10.1038/oncsis.2013.28 ID - Jung2013 ER - TY - JOUR AU - Lappe-Siefke, C. AU - Loebrich, S. AU - Hevers, W. AU - Waidmann, O. B. AU - Schweizer, M. AU - Fehr, S. PY - 2009 DA - 2009// TI - The ataxia (axJ) mutation causes abnormal GABAA receptor turnover in mice JO - PLoS Genet VL - 5 UR - https://doi.org/10.1371/journal.pgen.1000631 DO - 10.1371/journal.pgen.1000631 ID - Lappe-Siefke2009 ER - TY - JOUR AU - Lee, B. H. AU - Finley, D. AU - King, R. W. PY - 2012 DA - 2012// TI - A high-throughput screening method for identification of inhibitors of the deubiquitinating enzyme USP14 JO - Curr Protoc Chem Biol VL - 4 ID - Lee2012 ER - TY - JOUR AU - Hyrskyluoto, A. AU - Bruelle, C. AU - Lundh, S. H. AU - Do, H. T. AU - Kivinen, J. AU - Rappou, E. PY - 2014 DA - 2014// TI - Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1alpha JO - Hum Mol Genet VL - 23 UR - https://doi.org/10.1093/hmg/ddu317 DO - 10.1093/hmg/ddu317 ID - Hyrskyluoto2014 ER - TY - JOUR AU - Liu, N. AU - Li, X. AU - Huang, H. AU - Zhao, C. AU - Liao, S. AU - Yang, C. PY - 2014 DA - 2014// TI - Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth JO - Oncotarget VL - 5 ID - Liu2014 ER - TY - JOUR AU - Wu, N. AU - Zhang, C. AU - Bai, C. AU - Han, Y. P. AU - Li, Q. PY - 2014 DA - 2014// TI - MiR-4782-3p inhibited non-small cell lung cancer growth via USP14 JO - Cell Physiol Biochem Int J Exp Cell Physiol Biochem Pharmacol VL - 33 UR - https://doi.org/10.1159/000358626 DO - 10.1159/000358626 ID - Wu2014 ER - TY - JOUR AU - Wilson, S. M. AU - Bhattacharyya, B. AU - Rachel, R. A. AU - Coppola, V. AU - Tessarollo, L. AU - Householder, D. B. PY - 2002 DA - 2002// TI - Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease JO - Nat Genet VL - 32 UR - https://doi.org/10.1038/ng1006 DO - 10.1038/ng1006 ID - Wilson2002 ER - TY - JOUR AU - Crimmins, S. AU - Jin, Y. AU - Wheeler, C. AU - Huffman, A. K. AU - Chapman, C. AU - Dobrunz, L. E. PY - 2006 DA - 2006// TI - Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14 JO - J Neurosci VL - 26 UR - https://doi.org/10.1523/JNEUROSCI.3600-06.2006 DO - 10.1523/JNEUROSCI.3600-06.2006 ID - Crimmins2006 ER - TY - JOUR AU - Chen, P. C. AU - Qin, L. N. AU - Li, X. M. AU - Walters, B. J. AU - Wilson, J. A. AU - Mei, L. PY - 2009 DA - 2009// TI - The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions JO - J Neurosci VL - 29 UR - https://doi.org/10.1523/JNEUROSCI.2635-09.2009 DO - 10.1523/JNEUROSCI.2635-09.2009 ID - Chen2009 ER - TY - JOUR AU - Chen, P. C. AU - Bhattacharyya, B. J. AU - Hanna, J. AU - Minkel, H. AU - Wilson, J. A. AU - Finley, D. PY - 2011 DA - 2011// TI - Ubiquitin homeostasis is critical for synaptic development and function JO - J Neurosci VL - 31 UR - https://doi.org/10.1523/JNEUROSCI.2922-11.2011 DO - 10.1523/JNEUROSCI.2922-11.2011 ID - Chen2011 ER - TY - JOUR AU - Borodovsky, A. AU - Kessler, B. M. AU - Casagrande, R. AU - Overkleeft, H. S. AU - Wilkinson, K. D. AU - Ploegh, H. L. PY - 2001 DA - 2001// TI - A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14 JO - EMBO J VL - 20 UR - https://doi.org/10.1093/emboj/20.18.5187 DO - 10.1093/emboj/20.18.5187 ID - Borodovsky2001 ER - TY - JOUR AU - Michler, A. AU - Sakmann, B. PY - 1980 DA - 1980// TI - Receptor stability and channel conversion in the subsynaptic membrane of the developing mammalian neuromuscular junction JO - Dev Biol VL - 80 UR - https://doi.org/10.1016/0012-1606(80)90494-7 DO - 10.1016/0012-1606(80)90494-7 ID - Michler1980 ER - TY - JOUR AU - Kues, W. A. AU - Brenner, H. R. AU - Sakmann, B. AU - Witzemann, V. PY - 1995 DA - 1995// TI - Local neurotrophic repression of gene transcripts encoding fetal AChRs at rat neuromuscular synapses JO - J Cell Biol VL - 130 UR - https://doi.org/10.1083/jcb.130.4.949 DO - 10.1083/jcb.130.4.949 ID - Kues1995 ER - TY - JOUR AU - Bennett, E. J. AU - Shaler, T. A. AU - Woodman, B. AU - Ryu, K. Y. AU - Zaitseva, T. S. AU - Becker, C. H. PY - 2007 DA - 2007// TI - Global changes to the ubiquitin system in Huntington’s disease JO - Nature VL - 448 UR - https://doi.org/10.1038/nature06022 DO - 10.1038/nature06022 ID - Bennett2007 ER - TY - JOUR AU - Ikeda, F. AU - Dikic, I. PY - 2008 DA - 2008// TI - Atypical ubiquitin chains: new molecular signals. ‘Protein modifications: beyond the usual Suspects’ review series JO - EMBO Rep VL - 9 UR - https://doi.org/10.1038/embor.2008.93 DO - 10.1038/embor.2008.93 ID - Ikeda2008 ER - TY - JOUR AU - Jacobson, A. D. AU - Zhang, N. Y. AU - Xu, P. AU - Han, K. J. AU - Noone, S. AU - Peng, J. PY - 2009 DA - 2009// TI - The lysine 48 and lysine 63 ubiquitin conjugates are processed differently by the 26 s proteasome JO - J Biol Chem VL - 284 UR - https://doi.org/10.1074/jbc.M109.052928 DO - 10.1074/jbc.M109.052928 ID - Jacobson2009 ER - TY - JOUR AU - Xu, P. AU - Duong, D. M. AU - Seyfried, N. T. AU - Cheng, D. AU - Xie, Y. AU - Robert, J. PY - 2009 DA - 2009// TI - Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation JO - Cell VL - 137 UR - https://doi.org/10.1016/j.cell.2009.01.041 DO - 10.1016/j.cell.2009.01.041 ID - Xu2009 ER - TY - JOUR AU - Drerup, C. M. AU - Nechiporuk, A. V. PY - 2013 DA - 2013// TI - JNK-interacting protein 3 mediates the retrograde transport of activated c-Jun N-terminal kinase and lysosomes JO - PLoS Genet VL - 9 UR - https://doi.org/10.1371/journal.pgen.1003303 DO - 10.1371/journal.pgen.1003303 ID - Drerup2013 ER - TY - JOUR AU - Collins, C. A. AU - Wairkar, Y. P. AU - Johnson, S. L. AU - DiAntonio, A. PY - 2006 DA - 2006// TI - Highwire restrains synaptic growth by attenuating a MAP kinase signal JO - Neuron VL - 51 UR - https://doi.org/10.1016/j.neuron.2006.05.026 DO - 10.1016/j.neuron.2006.05.026 ID - Collins2006 ER - TY - JOUR AU - Costello, D. A. AU - Herron, C. E. PY - 2004 DA - 2004// TI - The role of c-Jun N-terminal kinase in the A beta-mediated impairment of LTP and regulation of synaptic transmission in the hippocampus JO - Neuropharmacology VL - 46 UR - https://doi.org/10.1016/j.neuropharm.2003.11.016 DO - 10.1016/j.neuropharm.2003.11.016 ID - Costello2004 ER - TY - JOUR AU - Bennett, B. L. AU - Sasaki, D. T. AU - Murray, B. W. AU - O’Leary, E. C. AU - Sakata, S. T. AU - Xu, W. PY - 2001 DA - 2001// TI - SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase JO - Proc Natl Acad Sci U S A VL - 98 UR - https://doi.org/10.1073/pnas.251194298 DO - 10.1073/pnas.251194298 ID - Bennett2001 ER - TY - JOUR AU - Zhang, Y. AU - Reckow, S. AU - Webhofer, C. AU - Boehme, M. AU - Gormanns, P. AU - Egge-Jacobsen, W. M. PY - 2011 DA - 2011// TI - Proteome scale turnover analysis in live animals using stable isotope metabolic labeling JO - Anal Chem VL - 83 UR - https://doi.org/10.1021/ac102755n DO - 10.1021/ac102755n ID - Zhang2011 ER - TY - JOUR AU - Moore, C. D. AU - Thacker, E. E. AU - Larimore, J. AU - Gaston, D. AU - Underwood, A. AU - Kearns, B. PY - 2007 DA - 2007// TI - The neuronal Arf GAP centaurin alpha1 modulates dendritic differentiation JO - J Cell Sci VL - 120 UR - https://doi.org/10.1242/jcs.006346 DO - 10.1242/jcs.006346 ID - Moore2007 ER - TY - JOUR AU - King, G. D. AU - Muhammad, A. K. AU - Larocque, D. AU - Kelson, K. R. AU - Xiong, W. AU - Liu, C. PY - 2011 DA - 2011// TI - Combined Flt3L/TK gene therapy induces immunological surveillance which mediates an immune response against a surrogate brain tumor neoantigen JO - Mol Ther J Am Soc Gene Ther VL - 19 UR - https://doi.org/10.1038/mt.2011.77 DO - 10.1038/mt.2011.77 ID - King2011 ER -