TY - CHAP AU - Wisniewski, H. M. AU - Terry, R. D. PY - 1973 DA - 1973// TI - Reexamination of the pathogenesis of the senile plaque BT - Prog Neuropathol ID - Wisniewski1973 ER - TY - CHAP AU - Dickson, D. W. AU - Farlo, J. AU - Davies, P. AU - Crystal, H. AU - Fuld, P. AU - Yen, S. H. PY - 1988 DA - 1988// TI - Alzheimer's disease. A double-labeling immunohistochemical study of senile plaques BT - Am J Pathol ID - Dickson1988 ER - TY - JOUR AU - Verkkoniemi, A. AU - Somer, M. AU - Rinne, J. O. AU - Myllykangas, L. AU - Crook, R. AU - Hardy, J. AU - Viitanen, M. AU - Kalimo, H. AU - Haltia, M. PY - 2000 DA - 2000// TI - Variant Alzheimer's disease with spastic paraparesis: clinical characterization JO - Neurology VL - 54 UR - https://doi.org/10.1212/WNL.54.5.1103 DO - 10.1212/WNL.54.5.1103 ID - Verkkoniemi2000 ER - TY - JOUR AU - Yang, A. J. AU - Knauer, M. AU - Burdick, D. A. AU - Glabe, C. PY - 1995 DA - 1995// TI - Intracellular A beta 1-42 aggregates stimulate the accumulation of stable, insoluble amyloidogenic fragments of the amyloid precursor protein in transfected cells JO - J Biol Chem VL - 270 UR - https://doi.org/10.1074/jbc.270.24.14786 DO - 10.1074/jbc.270.24.14786 ID - Yang1995 ER - TY - CHAP AU - Martin, B. L. AU - Schrader-Fischer, G. AU - Busciglio, J. AU - Duke, M. AU - Paganetti, P. Y. B. A. PY - 1995 DA - 1995// TI - Intracellular accumulation of beta-amyloid in cells expressing the Swedish mutant amyloid precursor protein BT - J Biol Chem ID - Martin1995 ER - TY - JOUR AU - Skovronsky, D. M. AU - Doms, R. W. AU - Lee, V. M. PY - 1998 DA - 1998// TI - Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture JO - J Cell Biol VL - 141 UR - https://doi.org/10.1083/jcb.141.4.1031 DO - 10.1083/jcb.141.4.1031 ID - Skovronsky1998 ER - TY - JOUR AU - D'Andrea, M. R. AU - Nagele, R. G. AU - Wang, H. Y. AU - Peterson, P. A. AU - Lee, D. H. PY - 2001 DA - 2001// TI - Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease JO - Histopathology VL - 38 UR - https://doi.org/10.1046/j.1365-2559.2001.01082.x DO - 10.1046/j.1365-2559.2001.01082.x ID - D'Andrea2001 ER - TY - JOUR AU - Gouras, G. K. AU - Tsai, J. AU - Naslund, J. AU - Vincent, B. AU - Edgar, M. AU - Checler, F. AU - Greenfield, J. P. AU - Haroutunian, V. AU - Buxbaum, J. D. AU - Xu, H. AU - Greengard, P. AU - Relkin, N. R. PY - 2000 DA - 2000// TI - Intraneuronal Abeta42 accumulation in human brain JO - Am J Pathol VL - 156 UR - https://doi.org/10.1016/S0002-9440(10)64700-1 DO - 10.1016/S0002-9440(10)64700-1 ID - Gouras2000 ER - TY - JOUR AU - Dickson, D. W. PY - 1997 DA - 1997// TI - The pathogenesis of senile plaques JO - J Neuropathol Exp Neurol VL - 56 UR - https://doi.org/10.1097/00005072-199704000-00001 DO - 10.1097/00005072-199704000-00001 ID - Dickson1997 ER - TY - JOUR AU - Terry, R. D. AU - Peck, A. AU - DeTeresa, R. AU - Schechter, R. AU - Horoupian, D. S. PY - 1981 DA - 1981// TI - Some morphometric aspects of the brain in senile dementia of the Alzheimer type JO - Ann Neurol VL - 10 UR - https://doi.org/10.1002/ana.410100209 DO - 10.1002/ana.410100209 ID - Terry1981 ER - TY - JOUR AU - Lue, L. F. AU - Kuo, Y. M. AU - Roher, A. E. AU - Brachova, L. AU - Shen, Y. AU - Sue, L. AU - Beach, T. AU - Kurth, J. H. AU - Rydel, R. E. AU - Rogers, J. PY - 1999 DA - 1999// TI - Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease JO - Am J Pathol VL - 155 UR - https://doi.org/10.1016/S0002-9440(10)65184-X DO - 10.1016/S0002-9440(10)65184-X ID - Lue1999 ER - TY - JOUR AU - McLean, C. A. AU - Cherny, R. A. AU - Fraser, F. W. AU - Fuller, S. J. AU - Smith, M. J. AU - Beyreuther, K. AU - Bush, A. I. AU - Masters, C. L. PY - 1999 DA - 1999// TI - Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease JO - Ann Neurol VL - 46 UR - https://doi.org/3.0.CO;2-M DO - 3.0.CO;2-M ID - McLean1999 ER - TY - JOUR AU - Haass, C. AU - Selkoe, D. J. PY - 2007 DA - 2007// TI - Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide JO - Nat Rev Mol Cell Biol VL - 8 UR - https://doi.org/10.1038/nrm2101 DO - 10.1038/nrm2101 ID - Haass2007 ER - TY - CHAP AU - Iwatsubo, T. AU - Odaka, A. AU - Suzuki, N. AU - Mizusawa, H. AU - Nukina, N. AU - Ihara, Y. PY - 1994 DA - 1994// TI - Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43) BT - Neuron ID - Iwatsubo1994 ER - TY - JOUR AU - Fukumoto, H. AU - Asami-Odaka, A. AU - Suzuki, N. AU - Iwatsubo, T. PY - 1996 DA - 1996// TI - Association of A beta 40-positive senile plaques with microglial cells in the brains of patients with Alzheimer's disease and in non-demented aged individuals JO - Neurodegeneration VL - 5 UR - https://doi.org/10.1006/neur.1996.0002 DO - 10.1006/neur.1996.0002 ID - Fukumoto1996 ER - TY - JOUR AU - Hrncic, R. AU - Wall, J. AU - Wolfenbarger, D. A. AU - Murphy, C. L. AU - Schell, M. AU - Weiss, D. T. AU - Solomon, A. PY - 2000 DA - 2000// TI - Antibody-mediated resolution of light chain-associated amyloid deposits JO - Am J Pathol VL - 157 UR - https://doi.org/10.1016/S0002-9440(10)64639-1 DO - 10.1016/S0002-9440(10)64639-1 ID - Hrncic2000 ER - TY - JOUR AU - O'Nuallain, B. AU - Wetzel, R. PY - 2002 DA - 2002// TI - Conformational Abs recognizing a generic amyloid fibril epitope JO - Proc Natl Acad Sci U S A VL - 99 UR - https://doi.org/10.1073/pnas.022662599 DO - 10.1073/pnas.022662599 ID - O'Nuallain2002 ER - TY - JOUR AU - Williams, A. D. AU - Sega, M. AU - Chen, M. AU - Kheterpal, I. AU - Geva, M. AU - Berthelier, V. AU - Kaleta, D. T. AU - Cook, K. D. AU - Wetzel, R. PY - 2005 DA - 2005// TI - Structural properties of Abeta protofibrils stabilized by a small molecule JO - Proc Natl Acad Sci U S A VL - 102 UR - https://doi.org/10.1073/pnas.0408582102 DO - 10.1073/pnas.0408582102 ID - Williams2005 ER - TY - JOUR AU - Kayed, R. AU - Head, E. AU - Thompson, J. L. AU - McIntire, T. M. AU - Milton, S. C. AU - Cotman, C. W. AU - Glabe, C. G. PY - 2003 DA - 2003// TI - Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis JO - Science VL - 300 UR - https://doi.org/10.1126/science.1079469 DO - 10.1126/science.1079469 ID - Kayed2003 ER - TY - JOUR AU - Baglioni, S. AU - Casamenti, F. AU - Bucciantini, M. AU - Luheshi, L. M. AU - Taddei, N. AU - Chiti, F. AU - Dobson, C. M. AU - Stefani, M. PY - 2006 DA - 2006// TI - Prefibrillar amyloid aggregates could be generic toxins in higher organisms JO - J Neurosci VL - 26 UR - https://doi.org/10.1523/JNEUROSCI.4809-05.2006 DO - 10.1523/JNEUROSCI.4809-05.2006 ID - Baglioni2006 ER - TY - JOUR AU - Harper, J. D. AU - Wong, S. S. AU - Lieber, C. M. AU - Lansbury, P. T. PY - 1997 DA - 1997// TI - Observation of metastable Abeta amyloid protofibrils by atomic force microscopy JO - Chem Biol VL - 4 UR - https://doi.org/10.1016/S1074-5521(97)90255-6 DO - 10.1016/S1074-5521(97)90255-6 ID - Harper1997 ER - TY - JOUR AU - Necula, M. AU - Kayed, R. AU - Milton, S. AU - Glabe, C. G. PY - 2007 DA - 2007// TI - Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct JO - J Biol Chem VL - 282 UR - https://doi.org/10.1074/jbc.M608207200 DO - 10.1074/jbc.M608207200 ID - Necula2007 ER - TY - JOUR AU - Lambert, M. P. AU - Barlow, A. K. AU - Chromy, B. A. AU - Edwards, C. AU - Freed, R. AU - Liosatos, M. AU - Morgan, T. E. AU - Rozovsky, I. AU - Trommer, B. AU - Viola, K. L. AU - Wals, P. AU - Zhang, C. AU - Finch, C. E. AU - Krafft, G. A. AU - Klein, W. L. PY - 1998 DA - 1998// TI - Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins JO - Proc Nat Acad Sci USA VL - 95 UR - https://doi.org/10.1073/pnas.95.11.6448 DO - 10.1073/pnas.95.11.6448 ID - Lambert1998 ER - TY - JOUR AU - von Bergen, M. AU - Friedhoff, P. AU - Biernat, J. AU - Heberle, J. AU - Mandelkow, E. M. AU - Mandelkow, E. PY - 2000 DA - 2000// TI - Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure JO - Proc Nat Acad Sci USA VL - 97 UR - https://doi.org/10.1073/pnas.97.10.5129 DO - 10.1073/pnas.97.10.5129 ID - von Bergen2000 ER - TY - CHAP AU - Lin, C. Y. AU - Gurlo, T. AU - Kayed, R. AU - Butler, A. E. AU - Haataja, L. AU - Glabe, C. G. AU - Butler, P. C. PY - 2007 DA - 2007// TI - Toxic Human IAPP Oligomers are Intracellular, and Vaccination to Induce Anti-toxic Oligomer Antibodies Does not Prevent Human IAPP Induced Beta-Cell Apoptosis in Human IAPP Transgenic Mice BT - Diabetes ID - Lin2007 ER - TY - JOUR AU - Chen, Y. R. AU - Glabe, C. G. PY - 2006 DA - 2006// TI - Distinct early folding and aggregation properties of Alzheimer amyloid-beta peptides Abeta40 and Abeta42: stable trimer or tetramer formation by Abeta42 JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M602363200 DO - 10.1074/jbc.M602363200 ID - Chen2006 ER - TY - JOUR AU - Kayed, R. AU - Glabe, C. G. PY - 2006 DA - 2006// TI - Conformation-dependent anti-amyloid oligomer antibodies JO - Methods Enzymol VL - 413 UR - https://doi.org/10.1016/S0076-6879(06)13017-7 DO - 10.1016/S0076-6879(06)13017-7 ID - Kayed2006 ER - TY - JOUR AU - Butler, A. E. AU - Janson, J. AU - Soeller, W. C. AU - Butler, P. C. PY - 2003 DA - 2003// TI - Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid JO - Diabetes VL - 52 UR - https://doi.org/10.2337/diabetes.52.9.2304 DO - 10.2337/diabetes.52.9.2304 ID - Butler2003 ER - TY - JOUR AU - Wang, B. AU - Larson, L. PY - 1985 DA - 1985// TI - Simultaneous demonstration of multiple antigens by indirect immunofluorescence or immunogold staining. JO - Histochemistry VL - 83 UR - https://doi.org/10.1007/BF00495299 DO - 10.1007/BF00495299 ID - Wang1985 ER -