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Figure 2 | Molecular Neurodegeneration

Figure 2

From: Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease

Figure 2

Quantification of neuronal levels of isoprostanes. A. Computer assisted image analysis reveals pyramidal neurons from cases of AD (n = 10) reveal significantly higher levels of 8-iso-PGF (p < 0.01) and13,14-dihydro 15-keto PGF (p < 0.001) than aged controls (n = 10). Mann-Whitney U-test. Data shown expresses mean +/- SEM. B. In the aged control cases, neuronal levels of 8-iso-PGF are significantly correlated with the numbers of AT8-positive NFT.

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