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Figure 2 | Molecular Neurodegeneration

Figure 2

From: Novel action of apolipoprotein E (ApoE): ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons

Figure 2

Time-dependent release of cholesterol and PC from cultured neurons in the presence of apoE3-HDL or apoE4-HDL. The kinetics of cholesterol and PC release in the presence of apoE3- or apoE4-HDL at a cholesterol concentration of 500 ng/ml were determined. Both apoE3- () and apoE4-HDL () induced cholesterol and PC release in a time-dependent manner. Data are means ± S.E. of four samples. *p < 0.001 and **p < 0.0001 vs apoE4-HDL. Six independent experiments showed similar results.

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