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Figure 1 | Molecular Neurodegeneration

Figure 1

From: Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice

Figure 1

Experimental Design. The frontal cortical (FC) and hippocampal (HC) transcriptome of PS1/PS2 double-knockout animals (KO) was compared to that of wild-type controls (WT) using Affymetrix oligonucleotide microarrays. The samples from 5 different ages for each microarray were prepared from a pool of 3 animals. Data were GCOS segmented, gcRMA normalized and compared using several experimental paradigms, all employing pairwise comparison statistics.

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