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Figure 1 | Molecular Neurodegeneration

Figure 1

From: A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation

Figure 1

A schematic representation of the human RNF182 gene, transcript and protein structures. Solid lines refer to introns or non-transcribed genomic DNA. Hatched bars represent exons. The RNF182 gene (GenBank AL138718) contains four exons. The open reading frame (black bar) and 3' untranslated region of both transcripts are solely encoded by exon 4. Structural motifs of the encoded protein were predicted by ExPASy tools.

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Molecular Neurodegeneration

ISSN: 1750-1326