A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation

Table 1 Description of brain samples used for qRT-PCR analysis of RNF182

Patient	Sex	Age	Postmortem	Pathology
Control 1	Male	89	9 hours	Normal
Control 2	Male	64	8 hours	Normal
Control 3	Male	63	8 hours	Normal
Control 4	Male	80	9.5 hours	Normal
Control 5	Male	95	11 hours	Normal
AD 1	Female	84	8 hours	Probable AD, according to CERAD
AD 2	Male	77	6 hours	Senile dementia of AD type
AD 3	Female	81	7.25 hours	Definite AD, possible multi-infarct dementia
AD 4	Male	74	6 hours	Senile changes of AD type
AD 5	Male	N/A	6 hour	Moderate senile changes of AD type, dementia

ISSN: 1750-1326