Skip to main content
Figure 2 | Molecular Neurodegeneration

Figure 2

From: Changes in γ-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1

Figure 2

The relative Aβ level secreted in the various stable cell lines treated with L-685,458.40 (A) and Aβ42 (B) were measured by ELISA 24 hours post treatment with the γ-secretase inhibitor L-685,458 (n = 2). The untreated samples were used for normalization. H125.3-16 (APP-Sw, ), APA2 (APP-Sw + PS1, ), APB10 (APP-Sw + PS1-D385TG, ), APC5 (APP-Sw + PS1-D257TG/D385TG, +), APD3 (APP-Sw + PS1-M146V, ▲) and H167-11 (APPV642F, □).

Back to article page