Figure 2

Treatments with Lithium and Rosiglitazone reduce the amount of total Aβ in brains of APPswe+PSEN1ΔE9 mice. (A) Hippocampal and cortical slices from transgenic mice APPswe+PSEN1ΔE9 (Tg) stained against Aβ. Photos are of Tg control and Tg treated animals with Lithium or Rosiglitazone. Figures B and C show the average Aβ plaque area (μm²) in the hippocampus and cortex after the treatments of lithium (B) and rosiglitazone (C) respectively, with bars representing the average plaque area for each specific treatment ± S.E (n = 5). Asterisks indicate significant differences, p < 0.05.