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Figure 4 | Molecular Neurodegeneration

Figure 4

From: Inducible mutant huntingtin expression in HN10 cells reproduces Huntington's disease-like neuronal dysfunction

Figure 4

Transcriptional abnormalities in proliferating and differentiated HN10 cells in the presence or absence of mutant huntingtin. A: mRNA determinations by real-time PCR of a selected panel of genes in mutant 72Q Htt-exon1 expressing and control proliferating HN10 cells. B: Same as in A using differentiated, non-dividing HN10 cells. C: Effect of differentiation of HN10 cells on transcription of the same genes. All graphs: n = 3, * p < 0.05*, ** p < 0.01, *** p < 0.001.

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