Aβ-transgenic C. elegans are protected from Cu2+ toxicity in motility assays. The graph represents the results of the thrashing assays (movement in liquid medium) performed on control and Aβ expressing worms after being cultured on regular agar or in copper supplemented agar for 72 or 168 h stating at the embryo stage. Statistical analysis: t-test to compare control worms (grey bars) with Aβ expressing worms (white bars) cultured on regular agar plates (no Cu2+) during 72 and 168 h. *** p < 0.001. t-test to compare control worms cultured on copper supplemented agar with control worms cultured on regular agar during 72 and 168 h. # p < 0.005, ### p < 0.001; and to compare Aβ worms cultured on copper supplemented agar (150 μM) with Aβ worms cultured on regular agar during 72 and 168 h. # p < 0.005, ### p < 0.001. Bars indicate standard error. See representative videos in Additional files 2 and 3.