From: Reduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy
PD (n = 6) | SEM |
PD vs PD+LLLT p value |
CNT (n = 5) | SEM |
PD vs CNT p value | |
---|---|---|---|---|---|---|
Velocity (μm/sec) | 0.175 | 0.005 | 0.001 | 0.232 | 0.017 | 0.02 |
Percent not moving (v<0.075) | 29 | 3.68 | 0.01 | 14 | 2.42 | 0.01 |
Average distance traveled | 0.54 | 0.016 | 0.006 | 0.757 | 0.048 | NS |
Total distance traveled | 9.92 | 0.261 | 0.004 | 17.09 | 1.18 | 0.004 |
Time spent moving (out of 120 sec) | 45 | 0.358 | NS | 61 | 6.89 | NS |
Number of neurites/cybrid | 24–53 | 26–44 | ||||
PD + LLLT
(n = 6) | SEM |
CNT + LLLT
(n = 5) | SEM |
CNT vs CNT+LLLT
p value | ||
LLLT-50 mW/cm^{2} for 40 sec (2J/cm^{2}) | ||||||
Velocity (μm/sec) | 0.224 | 0.02 | 0.226 | 0.017 | NS | |
Percent not moving (v<0.075) | 12 | 2.15 | 16 | 2.15 | NS | |
Average distance traveled | 0.682 | 0.033 | 0.782 | 0.065 | NS | |
Total distance traveled | 12.78 | 0.616 | 16.34 | 1.27 | NS | |
Time spent moving (out of 120 sec) | 48 | 3.94 | 63 | 6.92 | NS | |
Number of neurites/cybrid | 25–51 | 28–58 |