Reduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy

Table 1 Data from studies of mitochondrial movement in LLLT and untreated PD and CNT cybrid neurons

	PD (n = 6)	SEM	PD vs PD+LLLT p value	CNT (n = 5)	SEM	PD vs CNT p value
Velocity (μm/sec)	0.175	0.005	0.001	0.232	0.017	0.02
Percent not moving (v<0.075)	29	3.68	0.01	14	2.42	0.01
Average distance traveled	0.54	0.016	0.006	0.757	0.048	NS
Total distance traveled	9.92	0.261	0.004	17.09	1.18	0.004
Time spent moving (out of 120 sec)	45	0.358	NS	61	6.89	NS
Number of neurites/cybrid	24–53			26–44
	PD + LLLT (n = 6)	SEM		CNT + LLLT (n = 5)	SEM	CNT vs CNT+LLLT p value
LLLT-50 mW/cm² for 40 sec (2J/cm²)
Velocity (μm/sec)	0.224	0.02		0.226	0.017	NS
Percent not moving (v<0.075)	12	2.15		16	2.15	NS
Average distance traveled	0.682	0.033		0.782	0.065	NS
Total distance traveled	12.78	0.616		16.34	1.27	NS
Time spent moving (out of 120 sec)	48	3.94		63	6.92	NS
Number of neurites/cybrid	25–51			28–58

Significance was determined using a two-tailed t test assuming unequal variance.

ISSN: 1750-1326