Polymorphisms and haplotype blocks in PPARGC1A. Linear map with exons (full boxes), SNP positions are relative to the translational start site. MAF indicates minor allele frequency; typing studies in other populations showed that, unlike in the HD population studied, C > T at rs6821591; SNP qualifiers refer to database entries http://www.ncbi.nlm.nih.gov/SNP/. SNPs not used in the initial haplotyping studies are shown above the linear map. The extension of haplotype blocks is shown at the bottom. Scales differ for the transcribed sequence and the 5'-untranscribed sequence.