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Table 1 PPARGC1A Block 2 Haplotypes and Age at Onset of HD

From: The gene coding for PGC-1α modifies age at onset in Huntington's Disease

Haplotype Frequency Score P
0000 0.234 -2.766 0.0057
0001 0.139 2.633 0.0085
0011 0.080 0.038 0.9698
0111 0.324 -0.192 0.8479
1000 0.204 0.396 0.6923
  1. N = 389; adjusted for CAG repeat size on both alleles (HD and non-HD) and their interaction;
  2. P = 0.0161 for global haplotype statistics; block 2 haplotypes: 0, more common allele
  3. (+1302C, +1564C, +1704C, +2962C); 1, less common allele (+1302T, +1564T, +1704C, +2962T).