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Table 1 Summary of age, gender, PMI and Aβ load in the AD and age-matched controls brain tissues.

From: Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

Sample Age (years) Gender (M/F) PMI (hrs) Aβ Load
(scale 0–8)
AD     C F T
1 74 M N/A 2 8 8
2 72 M 18 0 8 8
3 87 M 4 0 4 6
4 83 M 5 0 8 8
5 84 M 2 1 4 4
6 88 M N/A 0 8 8
7 72 M 2 3 8 8
8 79 M 23 0 8 8
9 92 M 10 0 6 6
10 82 F 4 2 8 8
11 83 F 2 2 7 7
12 85 F 3 0 7 5
Average 81.7 +/- 6.3   7.3 0.8 7 7
Controls       
1 67 M 3 0 0 0
2 74 M N/A 0 2 0
3 87 F 24 0 3 3
4 62 M N/A 0 0 0
5 89 M 6 0 0 0
6 85 M 48 0 4 3
7 87 F 4 0 0 0
8 78 F 6 0 4 3
9 87 M 12 0 2 0
Average 79.5 +/- 9.9   14.7 0 1.7 1
  1. Table summarizes the post mortem intervals (PMI) and the Aβ load for each brain tissue specimen used. The plaque counts were performed in specific areas using semi-quantitative measures generated using CERAD methodology. They are purely estimates of pathology on a scale of 0–8. There was no statistically significant difference in age between groups by T-test. In the AD group, the majority is males since the samples were obtained from a VA hospital.
  2. C = Cerebellum; F = Frontal cortex; T = Temporal cortex; Gender: M = Male; F = Female; PMI = post mortem interval.