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Figure 2 | Molecular Neurodegeneration

Figure 2

From: Parkinson's disease brain mitochondria have impaired respirasome assembly, age-related increases in distribution of oxidative damage to mtDNA and no differences in heteroplasmic mtDNA mutation abundance

Figure 2

Levels of representative subunit proteins from Complexes II-V in sPD brain mitochondria. Individual protein band intensities were normalized to porin intensity in each sample and expressed in terms of mean CTL levels. A 2-way ANOVA across subunits and disease showed a significant interaction. Mann-Whitney test showed significant reductions for Complex IV subunit in sPD samples.

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Molecular Neurodegeneration

ISSN: 1750-1326