Distribution across mtDNA of inhibition of PCR amplification from treatment with hOGG1 as a function of donor age. mtDNA's from CTL and sPD brains were treated with hOGG1 and amplified with qPCR and primer pairs A-H. Shown are the proportional amplification for each sample and each primer pair. sPD samples showed (with one exception) an age-related in increase of hOGG1 sensitivity not seen in CTL samples. Donor ages for each sample are shown on the right.