Figure 4

Stereologic estimates of hippocampal subregions of TgCRND8 mice raised on various diets. HF, high fat custom chow; HC, high carbohydrate custom chow; HP, high protein custom chow; RC, regular commercial chow. Vertical bars are means ± SEMs. A) Neuronal counts (n = 20). B) Volume estimation by Cavalieri principle (n = 22). [N.B., diet groups are named by either major component only (HF, HP, HC) or by an abbreviation indicating both major and minor components (HF/LC, HP/LC, HC/LF); HF or HF/LC = high fat/low carbohydrate custom chow (60 kcal% fat/30 kcal% protein/10 kcal% carbohydrate); HP or HP/LC = high protein/low carbohydrate custom chow (60 kcal% protein/30 kcal% fat/10 kcal% carbohydrate); HC or HC/LF = high carbohydrate/low fat custom chow (60 kcal% carbohydrate/30 kcal% protein/10 kcal% fat)].