Table 4 Expression of SORL1 isoforms in human brain as a function of NIA-RI neuropathology classification.
From: Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain
SORL1 Isoform | NIA-RI | N | Mean ± SE | P Value |
|---|---|---|---|---|
Total SORL1 | Zero-Low | 22 | 2.023 ± 0.151 | 0.033 |
|  | Mod-High | 35 | 1.584 ± 0.128 |  |
FL-SORL1 | Zero-Low | 22 | 1.980 ± 0.150 | 0.031 |
|  | Mod-High | 35 | 1.540 ± 0.126 |  |
Delta-2-SORL1 | Zero-Low | 22 | 0.043 ± 0.003 | 0.826 |
|  | Mod-High | 35 | 0.044 ± 0.003 |  |
Delta-2-SORL1 (%) | Zero-Low | 22 | 2.25 ± 0.15 | 0.001 |
|  | Mod-High | 29 | 2.93 ± 0.13 |  |