From: Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

SORL1 ISOFORM | Rs661057 | N | Mean ± SE | P Value* |
---|---|---|---|---|

Total SORL1 | T/T | 18 | 2.249 ± 0.196 | <0.001 |

T/C | 30 | 1.383 ± 0.086 | <0.001* | |

C/C | 8 | 2.081 ± 0.295 | 0.552* | |

FL-SORL1 | T/T | 18 | 2.199 ± 0.195 | <0.001 |

T/C | 30 | 1.344 ± 0.084 | <0.001* | |

C/C | 8 | 2.033 ± 0.292 | 0.553* | |

Delta-2-SORL1 | T/T | 18 | 0.050 ± 0.003 | 0.017 |

T/C | 30 | 0.039 ± 0.002 | 0.007* | |

C/C | 8 | 0.048 ± 0.007 | 0.706* | |

Delta-2-SORL1 (%) | T/T | 18 | 2.36 ± 0.20 | 0.072 |

T/C | 30 | 2.88 ± 0.14 | ||

C/C | 8 | 2.46 ± 0.28 |