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Table 5 Expression of SORL1 isoforms in human brain as a function of rs661057 genotype.

From: Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

SORL1 ISOFORM Rs661057 N Mean ± SE P Value*
Total SORL1 T/T 18 2.249 ± 0.196 <0.001
  T/C 30 1.383 ± 0.086 <0.001*
  C/C 8 2.081 ± 0.295 0.552*
FL-SORL1 T/T 18 2.199 ± 0.195 <0.001
  T/C 30 1.344 ± 0.084 <0.001*
  C/C 8 2.033 ± 0.292 0.553*
Delta-2-SORL1 T/T 18 0.050 ± 0.003 0.017
  T/C 30 0.039 ± 0.002 0.007*
  C/C 8 0.048 ± 0.007 0.706*
Delta-2-SORL1 (%) T/T 18 2.36 ± 0.20 0.072
  T/C 30 2.88 ± 0.14  
  C/C 8 2.46 ± 0.28  
  1. For each isoform, the initial p value is the overall ANOVA p value, while the p values marked with asterisks refer to LSD post-hoc comparisons with the rs661057 T/T group.