Expresssion of LRP1 and NYGGF4 in Alzheimer disease. A. Expression of LRP1 and NYGGF4 in entorhinal cortex (BA28/36), comparing controls and subjects with AD. ***, p < 0.001 B. Expression of LRP1 and NYGGF4 as a function of neuritic plaque density. Plaque density scores are derived from counts across five cortical regions: 0, no neuritic plaques; 1, 1-6 plaques per mm2; 2, 7-12 plaques per mm2; and, 3, >12 neuritic plaques per mm2. ***, p < 0.001 for negative linear trend.