Figure 7From: Phospholipase A2inhibitors protect against prion and Aβ mediated synapse degenerationPrP82-146 increased activation of cPLA 2 in synapses. Correlation between the amounts of activated cPLA2 in synaptosomes isolated from primary cortical neurones 1 hour after the addition of varying concentrations of PrP82-146 and the amount of synaptophysin in cell extracts from primary cortical neurones incubated for 24 hours with the same concentrations of PrP82-146.Back to article page