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Figure 8 | Molecular Neurodegeneration

Figure 8

From: Phospholipase A2inhibitors protect against prion and Aβ mediated synapse degeneration

Figure 8

PAF receptor antagonists protected against PrP82-146 induced synapse degeneration. The synaptophysin content of cortical neurones pre-treated with a vehicle control (■), 1 μM ginkgolide B (), 2 μM Hexa-PAF () or 2 μM CV6209 (□) and subsequently incubated with varying concentrations of PrP82-146 for 24 hours. Values shown are the mean average amount of synaptophysin ± SD, n = 12.

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