Figure 8From: Phospholipase A2inhibitors protect against prion and Aβ mediated synapse degenerationPAF receptor antagonists protected against PrP82-146 induced synapse degeneration. The synaptophysin content of cortical neurones pre-treated with a vehicle control (■), 1 μM ginkgolide B (○), 2 μM Hexa-PAF (●) or 2 μM CV6209 (□) and subsequently incubated with varying concentrations of PrP82-146 for 24 hours. Values shown are the mean average amount of synaptophysin ± SD, n = 12.Back to article page