Distinct Aβ isoform patterns in FAD and SAD. The figure shows OPLS-DA on the two classes SAD and FAD using the data shown in figure 2. (A) Score plot for FAD (open diamonds) and SAD (open circles). (B) Loading and (C) variable importance on projection (VIP) plots for the Aβ fragments. The error bars in (C) represent a 95% confidence interval.