C-terminal-truncation enhanced the cytotoxicity of α-synuclein. Percentage of cell viability of PC12 cells added 21 μM of fresh or incubated α-Syn from n = 3 independent experiments. The results are expressed as a percentage of the value of "control" (PBS) (gray bar), which is set as 100%. Values are expressed as mean ± SD. Full-length α-Syn (white bar), and α-Syn119 (black bar).