Figure 5

Impact of C-terminal-truncated α-synuclein on the aggregation of full length of α-synuclein. 70 μM full-length α-Syn, 35 μM truncated variants or a mixture of 35 μM full-length α-Syn and 35 μM truncated variants (Syn110+WT, Syn119+WT, Syn133+WT) were incubated in PBS buffer, pH 7.4, with stirring at 37°C in the absence (white bar or gray bar) and presence of 280 μM PQQ (black bar). The light scattering at 500 nm was used to monitor the total aggregation. n = 3 and error bar = standard deviation.