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Table 1 Wnt-5a ligand induces the clustering of PSD-95, effect of Aβ oligomers: Immunofluoresce in mature hippocampal neurons of 21DIV, every treatment were by 1 h.

From: Wnt-5aoccludes Aβ oligomer-induced depression of glutamatergic transmission in hippocampal neurons

Treatments PSD-95 (Number of clusters in 100 μM of neurite)
Control 24 ± 3
Wnt-5a 46 ± 8*
Wnt-5a/sFRP 25 ± 4
9 ± 3*
Aβ/Wnt-5a 23 ± 2
Aβ/Wnt-5a/sFRP 11 ± 2*
  1. Aβ 1 μM, (n = 3). *P < 0.01 respect to the control