Figure 2
From: Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain
Human Aβ levels in APP23 mouse brain samples in the presence or absence of X11L. Quantification of human Aβ40 (left) and Aβ42 (right) in brain samples composed of the cerebral cortex, hippocampus and olfactory bulb from APP23 and APP23/X11L-Ko mice (5-6 months old) was performed by sELISA. Concentrations were normalized to tissue weight. The data were analyzed by Student's t test. Statistical significance is indicated with asterisks (n = 10; *, p < 0.05). The error bars are S.E.