Table 2 Demographic details of study cohort stratified with respect to CDR (Clinical Dementia Rating) groups.
From: Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?
Characteristics | Area | CDR 0 | CDR 0.5 | CDR 1 | CDR 2 | CDR 3 | CDR4-5 |
|---|---|---|---|---|---|---|---|
Total subjects* | Hipp | 18 | 13 | 9 | 9 | 12 | 12 |
Area 20 | 18 | 13 | 8 | 13 | 18 | 18 | |
Gender (men/women) | Hipp | 7/11 | 6/7 | 3/6 | 0/9 | 3/9 | 3/9 |
Area 20 | 6/12 | 7/6 | 3/5 | 1/12 | 7/11 | 8/10 | |
Age (years) | Hipp | 75.2 ± 3.5 | 85.4 ± 2.7 | 83.4 ± 3.4 | 87.9 ± 2.0 | 88.8 ± 1.7 | 85.0 ± 1.9 |
Area 20 | 77.0 ± 3.9 | 85.5 ± 2.8 | 85.6 ± 3.8 | 87.6 ± 2.0 | 86.2 ± 8.5 | 84.2 ± 2.5 | |
Brain pH | Hipp | 6.43 ± 0.04 | 6.43 ± 0.07 | 6.31 ± 0.1 | 6.38 ± 0.09 | 6.34 ± 0.05 | 6.39 ± 0.07 |
Area 20 | 6.42 ± 0.05 | 6.42 ± 0.07 | 6.35 ± 0.11 | 6.39 ± 0.08 | 6.43 ± 0.05 | 6.36 ± 0.05 | |
RNA integrity number (RIN) | Hipp | 6.6 ± 0.1 | 6.2 ± 0.1 | 6.2 ± 0.2 | 6.2 ± 0.2 | 6.1 ± 0.1 | 6.2 ± 0.1 |
Area 20 | 6.9 ± 0.1 | 6.9 ± 0.1 | 6.7 ± 0.2 | 6.3 ± 0.2 | 6.9 ± 0.2 | 6.3 ± 0.1 | |
Postmortem interval (minutes) | Hipp | 713 ± 137 | 393 ± 85 | 264 ± 39 | 336 ± 66 | 276 ± 40 | 332 ± 80 |
Area 20 | 574 ± 109 | 381 ± 91 | 325 ± 52 | 358 ± 64 | 244 ± 29 | 310 ± 73 |