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Figure 6 | Molecular Neurodegeneration

Figure 6

From: Presenilin-1 regulates induction of hypoxia inducible factor-1α: altered activation by a mutation associated with familial Alzheimer's disease

Figure 6

Normal activation by IGF-1 and insulin of PI3K/Akt in Psen1-/- fibroblasts. Immortalized fibroblast cell lines were treated with IGF-1 (A) or insulin (B) for the indicated times. Western blotting was performed for p-Akt (Ser473) followed by reprobing for total Akt. Panels show representative blots from experiments that were performed multiple times.

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Molecular Neurodegeneration

ISSN: 1750-1326