Figure 3
From: The biochemical aftermath of anti-amyloid immunotherapy
Gray matter of UCSD immunized cases separated by HPLC (C8 reverse-phase). The figure shows the HPLC chromatogram fractions that were investigated by Western blotting developed with anti-AĪ²40 and anti-AĪ²42 and CT9APP antibodies. The diagonal-hyphenated line represents the acetonitrile gradient. Lanes 10 contain the standards AĪ²40 or AĪ²42 synthetic peptides. A) and B), correspond to the neuropathologically confirmed AD cases # 19 and # 20, respectively. C) corresponds to the neuropathologically confirmed hippocampal sclerosis. m, AĪ² monomer; d, AĪ² dimer; t, AĪ² trimer.