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Table 1 Co-localization of the Wt APP-GFP protein with the endocytic markers Transferrin, Rab 5, and Rab 7.

From: Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated

  Wt APP-GFP co-localization coefficients (%)
  In cytoplasmic vesicles In cell (cytoplasmic vesicles and Golgi)
Transferrin 18.8 ± 0.3 34.5 ± 2.4
Rab 5 19.5 ± 0.7 30.3 ± 2.4
Rab 7 15.2 ± 1.2 36.6 ± 2.0
  1. The co-localization coefficients presented reflect the percentage of APP-GFP pixels co-localizing with Transferrin, Rab 5 or Rab 7 pixels, respectively, in cytoplasmic vesicles only or in total cell. Total number of pixels in the APP-GFP channel is taken as 100%. Values are mean ± SEM (n=10).