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Figure 8 | Molecular Neurodegeneration

Figure 8

From: Progranulin modulates zebrafish motoneuron development in vivoand rescues truncation defects associated with knockdown of Survival motor neuron 1

Figure 8

Validation of rescue effect of zfPGRN-A in SMA model: Average number of specified MN defects per affected side (n ≥ 50/group). Statistical analyses were performed with one-way ANOVA followed by student-Newman-keuls Multiple Comparisons Test (p < 0.001-***, p < 0.01-**, p < 0.05-*). Error bars represent s.e.m. Abbreviations: WT, wild type; zfPGRN-A, zebrafish PGRN-A mRNA; smn1-MO-co-injection of Morpholino directed against initiator ATG and Morpholino directed against 5'UTR.

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