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Figure 9 | Molecular Neurodegeneration

Figure 9

From: Progranulin modulates zebrafish motoneuron development in vivoand rescues truncation defects associated with knockdown of Survival motor neuron 1

Figure 9

Co-injection of zfPGRN-A mRNA exaggerated NRP1a-MO induced Cap MN defects particularly branching. (A, B) Embryos injected with NRP1a-MO and (C) co-injected with NRP1a-MO + 100 pg zfPGRN-A. Multiple exits (A, C), Branched motor axons (B and C), and displaced neurons (B, C) were observed. Abbreviations: ME, Multiple Exits; DN, Displaced Neurons; B, Branching. Scale Bar = 50 μm.

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Molecular Neurodegeneration

ISSN: 1750-1326