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Figure 3 | Molecular Neurodegeneration

Figure 3

From: Expression of human A53T alpha-synuclein in the rat substantia nigra using a novel AAV1/2 vector produces a rapidly evolving pathology with protein aggregation, dystrophic neurite architecture and nigrostriatal degeneration with potential to model the pathology of Parkinson's disease

Figure 3

Expression of transgenes in the striatum. Both GFP and human alpha-synuclein were widely expressed throughout the striatum 3 weeks following delivery of AAV1/2 to the substantia nigra. Scale bar in panel A is 500 μm.

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