α-Synuclein-induced activation of GSK-3β and Tau hyper-phosphorylation and parkin protection. A). Western blot analysis of striatal brain extracts on Nu-PAGE SDS 10% gel (Invitrogen) and B). Densitometry analysis showing GSK-3β activity. C). Western blot analysis showing different Tau epitopes and. B) densitometric analysis of immunoblots, Asterisk is significantly different, ANOVA, with Neumann Keuls multiple comparison N = 4, P < 0.05.