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Figure 5 | Molecular Neurodegeneration

Figure 5

From: NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration

Figure 5

SNOC treatment inactivates PTEN's lipid phosphatase activity. (A) Dose-dependent effect of SNOC on lipid phosphatase activity as determined by Malachite Green assay. Data presented are means based on five independent experiments. ** indicates p < 0.05 and *** indicates p < 0.005. (B) DTT treatment (10 mM) completely restores the PTEN's lipid phosphatase activity abolished by SNOC (300 μM).

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