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Figure 1 | Molecular Neurodegeneration

Figure 1

From: Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathy

Figure 1

Accumulation of ferritin in cultured HF skin fibroblasts. Confocal immunofluorescence microscopy was performed on cultured confluent wild-type (non-HF) (a-c) and HF (d-f) fibroblasts using antibodies against alpha-tubulin (a, d) and mutant FTL (b, e). Nuclei were stained by DAPI (blue). A merge of the alpha-tubulin (red) and mutant FTL (green) images is shown in c and f. Mutant FTL was observed only in HF fibroblasts, both in the cytoplasm and nucleus. Scale bars: 30 μm.

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Molecular Neurodegeneration

ISSN: 1750-1326