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Figure 3 | Molecular Neurodegeneration

Figure 3

From: Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathy

Figure 3

Expression of proteins of iron metabolism. Representative western blots showing the expression of: a) TfR-1, b) DMT1 (+/-) IRE, and c) FPN, in non-HF and HF fibroblasts. Results are the means and SD of three independent experiments. Densitometric analysis shows a significant decrease in TfR1 levels (d) and a significant increase in total levels of DMT1 isoforms (e) in HF compared to non-HF fibroblasts.(*p < 0.05). No significant changes in the levels of FPN (f) were observed.

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