Figure 3
From: α-synuclein induced synapse damage is enhanced by amyloid-β1-42
βSN reduced the αSN-induced loss of synaptophysin. The synaptophysin content of cortical neurons incubated with varying concentrations of αSN (●), αSN premixed with βSN (1:10)(□) or αSN premixed with human serum albumin (1:10)(■) for 24 hours. Values shown are the mean amount of synaptophysin (units) ± SD, n = 12. (*) = amount of synaptophysin significantly higher than in neurons incubated with the same concentration of αSN alone (P < 0.01).