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Table 2 Analysis of covariance of PGC1α rs7665116 in Italian HD patients

From: Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease

Model R2 ΔR2 P value
HD CAG 0.4444   < 0.0001*
HD CAG + PGC1α rs7665116    
   1-1 vs 1-2 vs 2-2 0.4682 0.0238 0.0172*
   1-1 vs 1-2 + 2-2 0.4681 0.0237 0.0045*
  1. The level of significance was set to P = 0.05; n = 312
  2. HD CAG expanded CAG allele in huntingtin