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Table 2 Analysis of covariance of PGC1α rs7665116 in Italian HD patients

From: Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease

Model

R2

ΔR2

P value

HD CAG

0.4444

 

< 0.0001*

HD CAG + PGC1α rs7665116

   

   1-1 vs 1-2 vs 2-2

0.4682

0.0238

0.0172*

   1-1 vs 1-2 + 2-2

0.4681

0.0237

0.0045*

  1. The level of significance was set to P = 0.05; n = 312
  2. HD CAG expanded CAG allele in huntingtin
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Molecular Neurodegeneration

ISSN: 1750-1326