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Table 5 Mean ages-at-onset of the different rs2970870 genotypes in HD patients with ≤ 55 CAGs

From: Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease

Genotype Number of patientsa Mean CAGexp (SE) Mean AAOb (SE)
T/T 262 44.9 (0.21) 46.37 (0.77)
T/C 404 44.5 (0.15) 48.19 (0.62)
C/C 118 45.4 (0.33) 43.67 (1.15)
  1. CAGexp, expanded CAG repeat number; SE, standard error; T, major allele g.-1437T; C, minor allele g.-1437C.
  2. an = 784.
  3. bt-test: Patients ≤ 60 CAG repeats and genotype C/C differ significantly from patients with T/T and T/C genotype (p = 0.0039).