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Figure 1 | Molecular Neurodegeneration

Figure 1

From: Generation and Characterization of a genetic zebrafish model of SMA carrying the human SMN2gene

Figure 1

Strategy for generating Tg(hSMN2) zebrafish. (A) Diagrammatic representation of the hSMN2:0.6hsp70:DsRed DNA construct. Arrows indicate the direction of expression. (B) Digestion of the hSMN2:0.6hsp70:DsRed construct using BamHI on 0.5% agarose gel. Lane 1, high molecular weight DNA ladder (Invitrogen); lane 2-3, two examples of the hSMN2:0.6hsp70:DsRed construct. (C) Transgenic larvae (3 dpf) as revealed by heat shocking.

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