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Figure 6 | Molecular Neurodegeneration

Figure 6

From: Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease

Figure 6

DA and its metabolites in striatal slices after rotenone treatment in wild-type (WT) and P2X 7 receptor knockout (KO) mice. Samples were analyzed using HPLC, and the amount of (A) dopamine (DA) 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), (B) norepinephrine, (NE), 3-methoxityramine (3-MT) and (C) 5-HT and 5-hydroxyindoleacetic acid (5-HIAA) is expressed in nmol/mg protein (n = 5-8). Asterisks indicate significant differences from the corresponding control (*P < 0.05, ** P < 0.01).

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